A new approach for the treatment of neuropathy (neuropatia)

Though there are numerous explanations for neuropathy (neuropatia), there are no direct treatment options or medication for this condition. Only very few strategies are available to reduce the discomfort of this condition. There are only a very limited number of drugs, which have been proven to be successful in its treatment.

Increasing the amount GABA is one such method of treatment for tingling in the hand (formigamento nas mãos). The GABA helps in decreasing the pain impulses travelling from hands to the brain, thereby diminishing the neuropathy pain. Another drug raises the neurotransmitters norepinephrine and serotonin. Similarly, some other drugs obstruct its receptors of glutamate and work to reduce the pain signaling. Even though much money has been spent in this regard and much research has been carried out, no single method has emerged out successful to help the sufferers of neuropathy. Most of the patients are not properly benefitted by these medications.

These days one new neurotransmitter along with its receptor is becoming the new found central figure in neuropathy research community. Amino acid glycine is considered as the new inhibitory neurotransmitter, which functions near the junction between neural cells popularly known as synapse. Introduction of glycine in this junction of two nerves halts the transmission of pain signals that travels to the brain. Therefore, glycine is named as inhibitory neurotransmitter. However glycine’s inhibition for pain signaling does not continue for long time since the nerve ends at the junction synapse have pumps that pump glycine out and clears the gap between nerves and sequester.

As a result, impulses like those in neuropathy start moving along its path form fingers and toes to the brain in the head making life unpleasant for persons affected by numbness in the hands (dormencia nas mãos). One study has shown that consumption of substantial amount of glycine can elevate the blood and cerebrospinal glycine percentages considerably.